• Guixa-Gonzalez R. Bruno A, Martí Solano M, Selent J. Crosstalk within GPCR heteromers in Schizophrenia and Parkinson’s disease: physical or just functional? Curr Med Chem 2012 ;19 :1119-34. PMID: 22300049


  • Selent J, Kaczor AA. Oligomerization of G protein-coupled receptors: biochemical and biophysical methods. Curr Med Chem 2011; 18(30):4606-34. PMID: 21864280

  • Selent J, Kaczor AA. Oligomerization of G protein-coupled receptors: computational methods. Curr Med Chem 2011 ;18(30): 4588-605. PMID: 21864281

  • Obiol-Pardo C. López L, Pastor M, and Selent J. Progress in the structural prediction of G protein-coupled receptors: D3 receptor in complex with eticlopride. Proteins 2011; 79(6): 1695-703. PMID: 21491496

  • Ortega R, Hübner H, Gmeiner P, Masaguer CF. Aromatic ring functionalization of benzolactam derivatives: new potent dopamine D3 receptor ligands.Bioorg Med Chem Lett. 2011 May 1;21(9):2670-4. PMID: 21273071

  • Barceló M, Raviña E, Varela MJ, Brea J, Loza MI, Masaguer CF. Potential atypical antipsychotics: synthesis, binding affinity and SAR of new heterocyclic bioisosteric butyrophenone analogues as multitarget ligands. Med Chem Commun 2011 ;2: 1194-1200. DOI: 10.1039/C1MD00202C


  • Selent J, Sanz F, Pastor M, Fabritiis G. Induced effects of sodium ions binding on dopaminergic G-protein coupled receptors. PLOS Computational Biology 2010; 6: pii:e1000884. PMID: 20711351

  • López L, Selent J, Ortega R, Masaguer CF, Domínguez E, Areias F, Brea J, Loza MI, Sanz F and Pastor M. Synthesis, 3D-QSAR and structural modeling of benzolactam derivatives with binding affinity for the D2 and D3 receptors ChemMedChem 2010; 5:1300-17 PMID: 20544783

  • Selent J, Bauer-Mehren A, López L, Loza MI, Sanz F, Pastor M. A novel multilevel statistical method for the study of the relationships between multireceptorial binding affinity profiles and in vivo endpoints. Mol Pharmacol 2010; 77(2):149-58 PMID: 19903829


  • Brea J, Castro M, Giraldo J, López-Giménez JF, Padín JF, Quintián F, Cadavid MI, Vilaró MT, Mengod G, Berg KA, Clarke WP, Vilardaga JP, Milligan G, Loza MI.
    Evidence for distinct antagonist-revealed functional states of 5-hydroxytryptamine(2A) receptor homodimers. Molecular Pharmacology. 2009; 75(6):1380-91. PMID: 19279328

  • Carro L, Raviña E, Dominguez E, Brea J, Loza MI, Masaguer CF. Synthesis and binding affinity of potential atypical antipsychotics with the tetrahydroquinazolinone motif. Bioorg Med Chem Lett 2009; 19 (21), 6059-6062. PMID: 19796944

  • Ortega R, Raviña E, Masaguer CF, Areias F, Brea J, Loza MI, Lopez L, Selent J, Pastor M, Sanz F. Synthesis, binding affinity and SAR of new benzolactam derivatives as dopamine D3 receptor ligands. Bioorg Med Chem Lett 2009; 19(6), 1773-1778. PMID: 19217777


  • Aranda R, Villalba K, Raviña E, Masaguer CF, Brea J, Areias F, Dominguez E, Selent J, Lopez L, Sanz F, Pastor M, Loza MI. Synthesis, Binding Affinity, and Molecular Docking Analysis of New Benzofuranone Derivatives as Potential Antipsychotics. J Med Chem 2008; 51(19), 6085-6094. PMID: 18783204


  • Domínguez E, Loza MI, Padín F, Gesteira A, Paz E, Páramo M, Brenlla J, Pumar E, Iglesias F, Cibeira A, Castro M, Caruncho H, Carracedo A, Costas J. Extensive linkage disequilibrium mapping at HTR2A and DRD3 for schizophrenia susceptibility genes in the Galician population. Schizoph Res 2007; 90(1-3):123-9. PMID: 17125970

  • Torrado M, Masaguer CF, Raviña E. Synthesis of substituted tetralones as intermediates of CNS agents via palladium-catalyzed cross-coupling reactions. Tetrahedron Letters 2007; 48:323-6. DOI:10.1016/j.tetlet.2006.10.154

  • Dezi C, Brea J, Alvarado M, Raviña E, Masaguer CF, Loza MI, Sanz F, Pastor M. Multi-structure 3D-QSAR studies on a series of conformationally constrained butyrophenones docked into a new homology model of the 5-HT2A receptor. J Med Chem. 2007;50(14):3242-55. PMID: 17579386

  • Barceló M, Raviña E, Masaguer C, Dominguez E, Areias F, Brea JM, Loza MI. Synthesis and Binding Affinity of New Pyrazole and Isoxazole Derivatives as Potential Atypical Antipsychotics. Bioorg Med Chem Lett 2007;17(17):4873-7. PMID: 17588750


  • Brea J, Castro M, Loza MI, Masaguer CF, Raviña E, Dezi C, Pastor M, Sanz F, Cabrero-Castel A, Galan-Rodriguez B, Fernandez-Espejo E, Maldonado R, Robledo P. QF2004B, a potential antipsychotic butyrophenone derivative with similar pharmacological properties to clozapine. Neuropharmacology 2006;51(2):251-62. PMID: 16697427

  • Alvarado M, Barceló M, Carro L, Masaguer CF, Raviña E. Synthesis and biological evaluation of new quinazoline and cinnoline derivatives as potential atypical antipsychotics. Chem Biodivers. 2006;3:106-17. PMID: 17193223