Conferences

2011

  • Carro L, Raviña E, Masaguer CF, Brea J, Loza MI. Synthesis and Biological Evaluation of Novel Conformationally Constrained Analogues of Haloperidol as CNS Agents. XVI Congress of the SEQT. Valencia, 18-21 Sept 2011.

  • Carro L, Masaguer CF, Raviña E, Brea J, Loza MI. Synthesis and Binding Affinity of Conformationally Constrained Butyrophenone Analogues of Haloperidol as Potential Atypical Antipsychotics 2nd Iberic Meeting on Medicinal Chemistry. Oporto, 12-15 June 2011

  • Insua I, Carro L, Masaguer CF, Brea J, Loza MI. Microwave-Assisted Synthesis of New Triazole Derivatives by Click Chemistry as Potential D3 Receptor Ligands. 2nd Iberic Meeting on Medicinal Chemistry. Oporto, 12-15 June 2011.

  • Obiol-Pardo C, López L, Pastor M, Selent J. Structure-based drug design: How accurately can we model G protein-coupled receptor complexes? The Modern Techniques for Drug Design Purposes. October 4th 2011, Warsaw, Poland.

  • Obiol-Pardo C, López L, Pastor M, Selent J. Successful prediction of G protein-coupled receptors: The eticlopride D3 receptor complex. CCG/MOE European User Group Meeting, September 27th 2011, Barcelona, Spain.

  • Obiol-Pardo C, López L, Pastor M, Selent J. Progresses and Challenges in the Prediction of GPCRs: D3 Receptor in Complex with Eticlopride. Membrane Proteins: Structure and Function, 6-8 April 2011, Oxford, England.

  • Kaczor AA, Carrió P, Guixá R, Obiol-Pardo C, Selent J, Pastor M. A Novel Approach For Predicting GPCR Oligomerization Based on Classical Protein-Protein Docking and Surface Roughness. Membrane Proteins: Structure and Function, 6-8 April 2011, Oxford, England.

  • Kaczor AA, Carrió P, Guixá R, Obiol-Pardo C, Pastor M, Selent J. Fractal Properties of GPCRs – Part I. Analysis of Surface Roughness. Membrane Proteins: Structure and Function, 6-8 April 2011, Oxford, England.

  • Kaczor AA, Carrió P, Guixá R, Obiol-Pardo C, Pastor M, Selent J. Fractal Properties of GPCRs – Part II. Identification of Classical and Novel Binding Sites. Membrane Proteins: Structure and Function, 6-8 April 2011, Oxford, England.

  • Kaczor AA, Carrió P, Guixá R, Obiol-Pardo C, Pastor M, Selent J. Fractal Properties of GPCRs – Part III. Is the Oligomerization Interface Smooth or Rough? Membrane Proteins: Structure and Function, 6-8 April 2011, Oxford, England.

  • Bruno A, Costantino G, Pastor M, Selent J. Effect of Membrane Composition on the Heterodimer mGluR2-5-HT2A Functionality and its Monomeric Subunits, Medicinal Chemistry in Drug Discovery: the Pharma Perspective. Summer School, San Lorenzo de el Escorial, 26-29 June 2011, Madrid, Spain.

  • Kaczor AA, Guixá R, Carrió P, Obiol-Pardo C, Pastor M, Selent J. Application of Fractal Dimension for Identification of Ligand-Protein Binding Interfaces: a Methodological Study. IV Konwersatorium Chemii Medycznej, 8-10 September 2011, Lublin, Poland.

2010

  • Raviña E, Masaguer CF, Loza MI, Brea J, Pastor M, Sanz F. Synthesis, Binding Affinity and SAR of New Heterocyclic Analogues of Haloperidol as Potential Atypical Antipsychotics. XXIst International Symposium on Medicinal Chemistry. 5-9 Sept 2010. Brussels, Belgium.

  • Ortega R, Masaguer CF, Huebner H, Gmeiner P. Aromatic Ring Functionalization of Benzolactam Derivatives: New Potent Dopamine D3 Receptor Ligands. XXIst International Symposium on Medicinal Chemistry, 5-9 Sept 2010. Brussels, Belgium.

  • Carro L, Raviña E, Masaguer CF, Loza MI, Brea J. Synthesis and Binding Affinity of New Tetralone Analogues of Haloperidol as Potential Atypical Antipsychotics. XXIst International Symposium on Medicinal Chemistry, 5-9 Sept 2010. Brussels, Belgium.

  • Selent J, Sanz F, Pastor M, De Fabritiis G. Sodium ions toggle the rotamer switch in sodium-sensitive dopaminergic G-protein coupled receptors, 28th Camerino-Cyprus-Noordwijkerhout Symposium. “Trekking through Receptor Chemistry”, May 16-20, 2010, Camerino, Italy.

  • Kaczor AA, López L, Pastor M and Selent J. Computational Approaches to the Prediction of G-Protein Coupled Receptors Oligomerization. 8th Annual Congress on International Drug Discovert Science and Technology. 2010. Beijin, China.

  • Kaczor AA, Pastor M and Selent J. Assessment of protein-protein docking tools for modeling oligomeric complexes of transmembrane proteins. 46th International Conference on Medicinal Chemistry: Interfacing Chemical Biology and Drug Discovery. 2010. Reims, France.

  • Kaczor AA, Pastor M and Selent J. Exploring dimerization interfaces on G protein coupled receptors. 46th International Conference on Medicinal Chemistry: Interfacing Chemical Biology and Drug Discovery. 2010. Reims, France.

  • Kaczor AA, López L, Pastor M and Selent J. Exploring G-protein coupled receptors oligomerization interface with adaptive Poisson-Boltzmann solver (APBS) XXIst International Symposium on Medicinal Chemistry, 2010, Bruselas, Bélgica

  • Kaczor AA, Selent J and Pastor M. Iterative protein-protein docking as a method for modeling G-protein coupled receptors dimers, XXIst International Symposium on Medicinal Chemistry, 2010, Bruselas, Bélgica

  • Selent J, Sanz F, Pastor M, De Fabritiis G. Allosteric modulation of GPCRs. Sodium ions act as fingertip toggling the rotamer switch. XXIst International Symposium on Medicinal Chemistry, 2010, Bruselas, Bélgica

2009

  • Selent J, Sanz F, Pastor M, De Fabritiis G. Molecular simulation of the sodium-induced allosteric effect in G-protein coupled receptors.Computational life sciences seminar, Pharmacy Centre, 25 November 2009, University of Vienna, Vienna, Austria.